Friday, January 24, 2020
Essay --
What is progeria? The word Progeria is a Greek word â€Å"progeros†meaning 'prematurely old' Progeria is a rare genetic disease that causes children to age faster than normal. Children with this disease do not show any symptoms at birth until after their first 10 months, after which their face and body will start to show accelerated retardation and resembles to that of an adult. Their head usually grows to that of an adult and their hair will start to disappear as they grow. Life average expectancy for children affected by this illness is usually between 13 to 20 years. Research shows the major causes of death of children affected by this disease is heart failure and stroke. Causes Symptoms Complications Preparing for your appointment Tests and diagnosis Treatments and drugs Lifestyle and home remedies Lifestyle and home remedies coping and support Causes Majority of children with this disease have a change in the gene that is responsible for encoding the LMNA in their bodies. LMNA is a gene that is responsible for producing a protein that helps maintain the structural integrity of the nucleus in human cells. When LMN A malfunctions certain nucleus in the body becomes unbalance. As a result of this malfunctioned nucleus, it is believed that the malfunctioned or the unbalanced proteins are the cause of progeria in children. Sometimes this disease occurs without any given cause. It sometimes occurs in a family that has not such history. While this disease affects the genes that helps our body to function there is no proven research which shows that it hereditary. Symptoms Children with this disorder are born normal at birth. They start to show characteristics of this disease before their first birthday. At this time they will start to... ...t blood clots. Growth hormone medication may also help the patient increase height and weight. Research also shows that there are steps parents and doctors can take to improve the quality of life for children affected by this disease. Example: since poor appetite is associate with this disease, parents are encourage to give certain nutritional supplements, like Pediasure and Boost to help patient get the nutrition and calories they need. Lifestyle and home remedies There are some steps parents can take at home that may help child affected by this disease. Parent should make sure to keep children with progeria stay warm and always hydrated. Dehydration can cause more harm to children affected with this disease. The child needs to always drink enough, more so whenever they are ill. They should always be provided with meals they are reach in nutrients and calories.
Thursday, January 16, 2020
Amma Unavagam
Growth through CARS Initiatives Pfizer is the world's largest and one of the most admired pharmacy companies with an income of about US $52 Ban in 2013. In 2001 when Dry Hank McKinley took over as Chairman and CEO of the company, Pfizer was very stable and financially sound. It was poised to become the world's largest pharmaceutical company with revenues doubling In the next five years. But the CEO had other serious challenges to contend with.In response to these challenges, Dry McConnell formulated a new mission of Pfizer to become the world's most valued company not Just to Investors, patients and customers but also, to employees, partners and communities where we live and work. †In line with this mission, Pfizer became the first pharmacy company and one the first corporate in the world to sign up for support for the LINE Global Compact (UNC). UNC among other things envisages that businesses should: 1. Support and respect the protection of internationally proclaimed human ri ghts and 2.Uphold the elimination of discrimination in respect of employment and occupation. To deliver on his commitments to these principles of UNC, Dry McKinley created and launched Its The Global Health Fellows Program (GAFF) In 2003 under his personal oversight. Under this program, Pfizer would send their skilled employees to developing countries on short term assignments (2 – 3 months) to help Noose there build health and social infrastructure in communities ravaged by various dreaded diseases.These employees would transfer their professional, medical and business expertise to the Noose in such a way that the Noose would learn to promote more efficient access to quality health services for the needy. Starting with mere 18 people in 2004, today over 300 Pfizer employees participate in assignments in 45 countries in partnerships with 40 international development organizations. Experience shows that through GAFF initiative, the MONGO partners gained expertise in capacity-b uilding analysis, planning and training that they couldn't otherwise afford.This helped them to Identify health trends and plan Interventions, enhanced their drug-trial competence helping them attract more western resources, and manage their programs better. International social cause as good corporate citizen. The Program became a personnel development tool. Returning volunteers came home with new operational and business insights as well as better understanding of the company's stakeholder including patients, communities, medical professionals and MONGO etc around the world especially in emerging markets.This in turn contributed to better policy making and program planning including bringing better AIDS therapies to the market. This program also served as a valuable recruitment and retention tool. It also helped build better relationships with legislative and regulatory authorities. Interestingly, the success of the GHB Program enthused Pfizer to include reports of philanthropic a ccess programs in their financial reports to the investors.
Tuesday, January 7, 2020
Talking on the Phone in Japanese
Even when you start to understand a language better, it is still difficult to use when talking on the phone. You cant use gestures, which can be helpful at times. Also, you cant see the other persons facial expressions or reactions to what you are saying. All of your efforts must be spent listening very carefully to what the other person is saying. Talking on the phone in Japanese might actually be harder than in other languages; since there are some formal phrases used specifically for phone conversations. The Japanese normally talk very politely on the phone unless speaking casually with a friend. Lets learn some common expressions used on the phone. Dont be intimidated by phone calls. Practice makes perfect! Phone Calls in Japan Most public phones (koushuu denwa) take coins (at least a 10 yen coin) and telephone cards. Only specially designated pay phones allow international calls (kokusai denwa). All calls are charged by the minute. Telephone cards can be purchased in almost all convenience stores, kiosks at train stations and vending machines. The cards are sold in 500 yen and 1000 yen units. Telephone cards can be customized. Occasionally companies even them as marketing tools. Some cards are very valuable and cost a fortune. Many people collect telephone cards in the same way postage stamps are collected. Telephone Number A telephone number consists of three parts. For example: (03) 2815-1311. The first part is the area code (03 is Tokyos), and the second and last part are the users number. Each number is usually read separately and the parts are linked with the particle, no. To reduce confusion in telephone numbers, 0 is often pronounced as zero, 4 as yon, 7 as nana and 9 as kyuu. This is because 0, 4, 7 and 9 each have two different pronunciations.The number for directory enquiries (bangou annai) is 104. The most essential telephone phrase is, moshi moshi. It is used when you receive a call and pick up the phone. It is also used when one cant hear the other person well, or to confirm if the other person is still on the line. Although some people say, moshi moshi to answer the phone, hai is used more often in business. If the other person speaks too fast, or you couldnt catch what he/she said, say, Yukkuri onegaishimasu (Please speak slowly) or Mou ichido onegaishimasu (Please say it again). Onegaishimasu is a useful phrase to use when making a request. At the Office Business phone conversations are extremely polite. Yamada-san (o) onegaishimasu. Ã¥ ± ±Ã§â€ °Ã£ •ã‚“ã‚’ã Šé ¡ËœÃ£ „ã â€"㠾ã â„¢Could I speak to Mr. Yamada?Moushiwake arimasen ga, tadaima gaishutsu shiteorimasu. 熳ã â€"è ¨ ³Ã£ ‚り㠾㠛んã Å'ã Ÿã 㠄㠾å ¤â€"å‡ ºÃ£ â€"㠦㠊り㠾ã â„¢Im sorry, but hes not here at the moment.Shou shou omachi kudasai. Ã¥ °â€˜Ã£â‚¬â€¦Ã£ Šå ¾â€¦Ã£ ¡Ã£ ã ã •ã „Just a moment, please.Shitsurei desu ga, dochira sama desu ka. Ã¥ ¤ ±Ã§ ¤ ¼Ã£ §Ã£ ™ã Å'㠩㠡ら㠕㠾㠧㠙㠋Whos calling, please?Nanji goro omodori desu ka. ä ½â€¢Ã¦â„¢â€šÃ£ â€Ã£â€š ã Šæˆ »Ã£â€šÅ 㠧㠙㠋Do you know what time he/she will be back?Chotto wakarimasen. 㠡ょ㠣㠨分㠋り㠾㠛んIm not sure.Mousugu modoru to omoimasu. も㠆㠙ã æˆ »Ã£â€šâ€¹Ã£ ¨Ã¦â‚¬ 㠄㠾ã â„¢He/she should be back soon.Yuug ata made modorimasen. Ã¥ ¤â€¢Ã¦â€" ¹Ã£ ¾Ã£ §Ã¦Ë† »Ã£â€šÅ 㠾㠛んHe/she wont be back till this evening.Nanika otsutae shimashou ka. ä ½â€¢Ã£ ‹ã Šä ¼ ã ˆã â€"㠾ã â€"ょ㠆㠋Can I take a message?Onegaishimasu. ã Šé ¡ËœÃ£ „ã â€"㠾ã â„¢Yes, please.Iie, kekkou desu. ã „ã „ã ˆç µ æ §â€¹Ã£ §Ã£ â„¢No, its O.K.O-denwa kudasai to otsutae negaemasu ka. ã Šé› »Ã¨ © ±Ã£ ã 㠕㠄㠨ã Šä ¼ ã ˆé ¡ËœÃ£ ˆã ¾Ã£ ™ã ‹Could you please ask him/her to call me?Mata denwa shimasu to otsutae kudasai. 㠾ã Ÿé› »Ã¨ © ±Ã£ â€"㠾㠙㠨ã Šä ¼ ã ˆã ã ã •ã „Could you please tell him/her Ill call back later? To Somebodys Home Tanaka-san no otaku desu ka. 熰ä ¸ 㠕ん㠮ã Šå ®â€¦Ã£ §Ã£ ™ã ‹Is that Mrs. Tanakas residence?Hai, sou desu. 㠯ã „ã 㠆㠧ã â„¢Yes, it is.Ono desu ga, Yuki-san (wa) irasshaimasu ka. Ã¥ ° 野㠧ã ™ã Å'ゆã 㠕ん㠯ã „ら㠣ã â€"ã‚Æ'㠄㠾㠙㠋This is Ono. Is Yuki there?Yabun osokuni sumimasen. Ã¥ ¤Å"分é …ã 㠫㠙㠿㠾㠛んIm sorry for calling so late.Dengon o onegaishimasu. ä ¼ è ¨â‚¬Ã£â€šâ€™Ã£ Šé ¡ËœÃ£ „ã â€"㠾ã â„¢Can I leave a message?Mata atode denwa shimasu. 㠾ã Ÿå ¾Å'㠧é› »Ã¨ © ±Ã£ â€"㠾ã â„¢Ill call back later. How to Deal With a Misdial Iie chigaimasu. ã „ã „ã ˆé •ã „ã ¾Ã£ â„¢No, you have called the wrong number.Sumimasen. Machigaemashita. 㠙㠿㠾㠛ん éâ€"“é •ã ˆã ¾Ã£ â€"ã ŸIm sorry. I have misdialed.
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